Outcome · Governed Data Ingestion

Every Instrument Connected. Every File Converted. Every Field Enriched.

Governed data ingestion connects instruments from 150+ vendors and 400+ models, converts proprietary formats into standardized scientific data, and enriches metadata beyond vendor limits — automatically, at scale, from Day 1.

The innovations described in the content herein are subject to patent rights present within a global patent portfolio developed and managed for the benefit of ZONTAL. All rights reserved.

Immediate Impact — What Changes After Go-Live
150+ Vendor instruments supported through Integration Factory
400+ Instrument models with governed converters
100+ Technique applications across analytical disciplines
Days Per instrument — down from weeks of custom work
The Challenge

Onboarding New Instruments Takes Too Long

Every new instrument model requires weeks of custom integration work. Each vendor exports data in a proprietary format with unique file structures and metadata schemas, forcing teams to build bespoke parsers one at a time. Critical metadata is lost in translation, and every firmware update risks breaking existing connections. The result: a growing backlog of disconnected instruments and ungoverned data.

What the Infrastructure Delivers

From Raw Instrument Output to Governed Scientific Data

Four products work together to transform instrument onboarding from a months-long IT project into a repeatable, governed workflow.

1 Integrate

Integration Factory Produces Converters

The Integration Factory produces validated converters for new instrument models at an accelerating pace. Each converter handles extraction, parsing, and format normalization — built once, reused across every site that runs that instrument. Every adapter includes simulation mode: the full build and verify cycle runs without a physical instrument connection, so converter development never competes with production for hardware access.

Product: Integration Factory · Integrations Catalog
2 Integrate

Data Hub Converts and Enriches

Data Hub receives raw instrument output, applies the appropriate converter, and enriches the result with metadata that goes beyond what the vendor provides — run parameters, calibration context, method references, and instrument identifiers.

Product: Data Hub · Technique Applications
3 Integrate + Contextualize

Fleet Dashboard Monitors Health

Fleet Dashboard provides real-time operational visibility across all connected devices — ingestion success rates, failure classification, device status, and data volume trending. Your operations team monitors fleet health, not ticket queues.

Product: Fleet Dashboard
4 Contextualize

IP Lifecycle Governance

Every Information Package follows a governed lifecycle from ingest to archive. Data is validated against its profile, classified by type, and tracked through each state — New, Submitted, Archived — with full provenance at every step.

Product: Scientific Context & Lineage
Fleet & Data Management

Thousands of Instruments, One Dashboard

Operational fleet monitoring and data management dashboards — device health, ingestion success rates, and failure classification across your entire instrument landscape.

ZONTAL Fleet Management Dashboard showing service overview at 87% online, device overview at 87% active, device ingest trend with 243,277 total at 91.6% success rate, and operational detail table with device status and health indicators
Fleet Management Dashboard — Service overview (87% online), device health monitoring, daily ingest trend (243K total, 91.6% success rate), and per-device operational detail with last submission time, health status, and error tracking.
ZONTAL Data Management Dashboard showing IPP volumes by profile (Stability, NMR, Release Test, Chromatography), data volume by format (RAW, CDF, PDF, CSV at 8.6 TB total), ingest failure timeline, and IPP health table with success rates
Data Management Dashboard — Information Package volumes by profile (Stability, NMR, Chromatography), data volume by format (8.6 TB across RAW, CDF, PDF, CSV), ingest failure tracking, and per-IPP health table with success rates and load times.
Quantified Results

Operational Impact from Day 1

Governed data ingestion transforms how labs connect instruments, monitor fleet health, and maintain data lineage across the entire instrument landscape.

Weeks → Days
Integration Time per Instrument

New instrument models go from weeks of custom integration to days of standardized onboarding through the Integration Factory.

Real-Time
Fleet Health Monitoring

Device status, ingestion success rates, and failure classification across every connected instrument — visible in a single operational pane.

Full Lineage
IP Lifecycle Tracking

Every Information Package tracked from ingest to archive with complete provenance — instrument, method, sample, batch, and program context.

Compound Effect

How Governed Ingestion Creates a Reusable Foundation

Governed data ingestion spans the first two principles. Integration industrializes instrument connectivity; the context engine contextualizes every data point into the scientific knowledge graph.

Every governed data point you ingest today builds the AI-ready foundation for tomorrow. AI models require validated, contextualized scientific data — not raw instrument files.
Evaluate readiness with the five-question framework →

Integrate

Integration Industrialization

Data Hub connects 150+ vendors and 400+ instrument models through governed Integration Factories. Every data point is validated and traced from source instrument to scientific context with full provenance. Integration Factories produce governed converters at scale. Fleet Dashboard monitors operational health across every connected device in real time.

  • 150+ vendor instruments supported
  • 400+ instrument models connected
  • 8 core techniques · 80+ variants
  • Fleet Dashboard monitors operational health across every connected device
Contextualize

Scientific Context & Lineage

Digital Lab and Platform Modules build the scientific context graph — ontology mapping, cross-system identity reconciliation, and full lineage from instrument through result to insight. Every ingested data point is contextualized within the scientific context graph. Lineage construction starts at ingestion — Contextualize depends on governed Integrate data quality.

  • Ontology mapping across all data domains
  • Cross-system identity reconciliation
  • Full lineage graph: instrument → method → sample → result
  • Provenance tracking from raw instrument data to scientific context
Webinar

Validated by Industry Leaders

Published content from pharmaceutical and agrochemical companies solving real scientific data challenges.

Solutions

How This Outcome Applies Across Scientific Domains

Discovery Biology

High-Volume Assay Data at Scale

Discovery biology workflows generate some of the largest datasets in pharma R&D — flow cytometry population files, high-content screening (HCS) image sets at 5 TB per experiment, plate reader kinetic curves across thousands of wells. Governed ingestion pipelines handle these volumes with full lineage from instrument to analysis, preserving scientific context that manual file transfers lose.

  • Flow cytometry, plate reader, and mass spectrometry data ingested at scale
  • High-content screening datasets (5 TB/file) with complete audit trails
  • Dose-response and IC50 calculations linked to raw instrument data
  • Compound-target assay relationships preserved through the context model
M&A Data Harmonization

Preserving Scientific Context During Organizational Transitions

When two organizations merge, their instrument fleets, Laboratory Information Management System (LIMS) instances, and Electronic Lab Notebook (ELN) systems must converge into a single governed data infrastructure. Governed data ingestion provides the framework: cross-system reconciliation, entity resolution, and audit trail preservation — without losing the scientific lineage that makes the data valuable.

  • Cross-system data harmonization preserving scientific lineage
  • Entity resolution across duplicate instrument and sample records
  • Audit trail continuity through organizational boundary changes
  • Master data management for merged instrument fleets
External Collaboration

Governed Data Exchange Across Organizational Boundaries

Pharmaceutical companies routinely outsource substantial portions of development work to Contract Research Organizations (CROs) and Contract Development and Manufacturing Organizations (CDMOs). When outsourced data arrives without governance, lineage, or standard formats, teams spend weeks reconciling before analysis can begin.

Auditable Cross-Organization Data Exchange

Governed ingestion pipelines apply the same validation, format standardization, and audit trail requirements to data from external partners as from internal instruments. CRO-generated chromatography runs, stability time points, and method validation results enter the platform with full provenance — no reconciliation required.

  • Same validation rules for internal and external data sources
  • Full audit trail from CRO instrument to your scientific context graph
  • Allotrope Simple Model (ASM) and vendor-neutral formats eliminate CRO-specific data wrangling

No Platform Dependency for Partners

External partners do not need to adopt ZONTAL. Integration Factories produce governed data converters that accept raw instrument outputs, proprietary vendor formats, and PDF from CRO and CDMO instrument fleets — and convert them into vendor-neutral formats on arrival. Your partners export data however they already do; the factory handles the rest.

  • CROs and CDMOs export raw outputs, proprietary formats, and PDF
  • Factory-built converters transform into vendor-neutral, governed formats
  • Zero software deployment required at partner sites

Cross-Site Regulatory Traceability

When outsourced studies contribute to regulatory submissions — Investigational New Drug (IND) applications, Chemistry, Manufacturing, and Controls (CMC) dossiers, or method transfers — every data point must trace back to its source instrument and conditions. Governed ingestion preserves that lineage across organizational boundaries, not just across internal sites.

  • Lineage preserved from CRO/CDMO instruments through to regulatory submissions
  • 21 CFR Part 11 compliant audit trails across organizational boundaries
  • Tech transfer packages include full provenance from external partner data

Trusted by 6 of the 10 largest pharmaceutical companies in the world

And leading biotechs and agrochemical companies

“There has been a process of democratization of data. It is really easy, possible to access and to find information. And that’s a huge benefit.”

Ralph Haefeli, Global Head Technical Research and Development IT, Novartis
Start With Your Data

Build the Foundation for Governed Data Ingestion

Connect your instruments, convert proprietary formats, and monitor fleet health — from Day 1. Talk to our team about what governed ingestion looks like for your lab.